Publication


1. Gho YS, Kim OY. Extracellular vesicles from Gram-negative and Gram-positive bacteria. Experimental Medicine. 34(9):1402-1404, 2016 [Off-line version only]

2. Lässer C, O'Neil SE, Shelke GV, Sihlbom C, Hansson SF, Gho YS, Lundbäck B, Lötvall J. Exosomes in the nose induce immune cell trafficking and harbor an altered protein cargo in chronic airway inflammation. Journal of Translational Medicine. 14(1):181, 2016

3. Sung YH, Baek IJ, Kim YH, Gho YS, Oh SP, Lee YJ, Lee HW. PIERCE1 is critical for specification of left-right asymmetry in mice. Scientific Reports. 6:27932, 2016

Wang T, Jang WH, Lee S, Yoon CJ, Lee JH, Kim B, Hwang S, Hong CP, Yoon Y, Lee G, Le VH, Bok S, Ahn GO, 4. Lee J, Gho YS, Chung E, Kim S, Jang MH, Myung SJ, Kim MJ, So PT, Kim KH. Moxifloxacin: Clinically compatible contrast agent for multiphoton imaging. Scientific Reports. 6:27142, 2016

5. Jeong D, Han C, Kang I, Park HT, Kim J, Ryu H, Gho YS, Park J. Effect of concentrated fibroblast-conditioned media on in vitro maintenance of rat primary hepatocyte. PLoS One. 11(2):e0148846, 2016

6. Bin BH, Kim DK, Kim NH, Choi EJ, Bhin J, Kim ST, Gho YS, Lee AY, Lee TR, Cho EG. Fibronectin-containing extracellular vesicles protect melanocytes against ultraviolet radiation-induced cytotoxicity. Journal of Investigative Dermatology. 136(5):957-966, 2016

7. Lener T, Gimona M, Aigner L, Börger V, Buzas E, Camussi G, Chaput N, Chatterjee D, Court FA, Del Portillo HA, O'Driscoll L, Fais S, Falcon-Perez JM, Felderhoff-Mueser U, Fraile L, Gho YS, Görgens A, Gupta RC, Hendrix A, Hermann DM, Hill AF, Hochberg F, Horn PA, de Kleijn D, Kordelas L, Kramer BW, Krämer-Albers EM, Laner-Plamberger S, Laitinen S, Leonardi T, Lorenowicz MJ, Lim SK, Lötvall J, Maguire CA, Marcilla A, Nazarenko I, Ochiya T, Patel T, Pedersen S, Pocsfalvi G, Pluchino S, Quesenberry P, Reischl IG, Rivera FJ, Sanzenbacher R, Schallmoser K, Slaper-Cortenbach I, Strunk D, Tonn T, Vader P, van Balkom BW, Wauben M, Andaloussi SE, Théry C, Rohde E, Giebel B. Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper. Journal of Extracellular Vesicles. 4:30087, 2015

8. Oh K, Kim SR, Kim DK, Seo MW, Lee C, Lee HM, Oh JE, Choi EY, Lee DS*, Gho YS*, Park KS*. In vivo differentiation of therapeutic insulin-producing cells from bone marrow cells via extracellular vesicle-mimetic nanovesicles. ACS Nano 9(12):11718-11727, 2015 (*co-corresponding authors)

8. Choi Y, Kwon Y, Kim DK, Jeon J, Jang SC, Wang T, Ban M, Kim MH, Jeon SG, Kim MS, Choi CS, Jee YK, Gho YS, Ryu SH, Kim YK. Gut microbe-derived extracellular vesicles induce insulin resistance, thereby impairing glucose metabolism in skeletal muscle. Scientific Reports. 5:15878, 2015

10. Hwang DW, Choi H, Jang SC, Yoo MY, Park JY, Choi NE, Oh HJ, Ha S, Lee YS, Jeong JM, Gho YS*, Lee DS*. Noninvasive imaging of radiolabeled exosome-mimetic nanovesicle using 99mTc-HMPAO. Scientific Reports. 5:15636, 2015 (*co-corresponding authors)

11. Lee WH, Choi HI, Hong SW, Kim KS, Gho YS, Jeon SG. Vaccination with Klebsiella pneumoniae-derived extracellular vesicles protects against bacteria-induced lethality via both humoral and cellular immunity. Experimental & Molecular Medicine. 47:e183, 2015

12. Choi SJ, Kim MH, Jeon J, Kim OY, Choi Y, Seo J, Hong SW, Lee WH, Jeon SG, Gho YS, Jee YK, Kim YK. Active immunization with extracellular vesicles derived from Staphylococcus aureus effectively protects against staphylococcal lung infections, mainly via Th1 cell-mediated immunity. PLoS One. 10(9):e0136021, 2015

13. Shin H, Han C, Labuz JM, Kim J, Kim J, Cho S, Gho YS, Takayama S, Park J. High-yield isolation of extracellular vesicles using aqueous two-phase system. Scientific Reports. 5:13103, 2015

14. Kim B, Lee SH, Yoon CJ, Gho YS, Ahn GO, Kim KH. In vivo visualization of skin inflammation by optical coherence tomography and two-photon microscopy. Biomedical Optics Express. 6(7):2512-2521, 2015

15. Lee J, Kim SH, Choi DS, Lee JS, Kim DK, Go G, Park SM, Kim SH, Shin JH, Chang CL, Gho YS. Proteomic analysis of extracellular vesicles derived from Mycobacterium tuberculosis. Proteomics. 15(19):3331-3337, 2015 [Cover story]

16. Lunavat TR, Cheng L, Kim DK, Bhadury J, Jang SC, Lässer C, Sharples RA, López MD, Nilsson J, Gho YS, Hill AF, Lötvall J. Small RNA deep sequencing discriminates subsets of extracellular vesicles released by melanoma cells - Evidence of unique microRNA cargos. RNA Biology. 12(8):810-823, 2015

17. Minciacchi VR, You S, Spinelli C, Morley S, Zandian M, Aspuria PJ, Cavallini L, Ciardiello C, Reis Sobreiro M, Morello M, Kharmate G, Jang SC, Kim DK, Hosseini-Beheshti E, Tomlinson Guns E, Gleave M, Gho YS, Mathivanan S, Yang W, Freeman MR, Di Vizio D. Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles. Oncotarget. 6(13):11327-11341, 2015

18. Choi DS, Gho YS. Isolation of extracellular vesicles for proteomic profiling. Methods in Molecular Biology. 1295:167-177, 2015

19. Kim YS, Lee WH, Choi EJ, Choi JP, Heo YJ, Gho YS, Jee YK, Oh YM, Kim YK. Extracellular vesicles derived from Gram-negative bacteria, such as Escherichia coli, induce emphysema mainly via IL-17A-mediated neutrophilic inflammation. Journal of Immunology. 194(7):3361-3368, 2015

20. Kim DK, Lee J, Simpson RJ, Lötvall J, Gho YS. EVpedia: A community web resource for prokaryotic and eukaryotic extracellular vesicles research. Seminars in Cell & Developmental Biology. 40: 4-7, 2015 [Invited review]

21. Kim JH, Lee J, Park J, Gho YS. Gram-negative and Gram-positive bacterial extracellular vesicles. Seminars in Cell & Developmental Biology. 40: 97-104, 2015 [Invited review]

22. Lee JH, Lee S, Gho YS, Song IS, Tchah H, Kim MJ, Kim KH. Comparison of confocal microscopy and two-photon microscopy in mouse cornea in vivo. Experimental Eye Research. 132C:101-108, 2015

23. Lötvall J, Hill AF, Hochberg F, Buzás EI, Di Vizio D, Gardiner C, Gho YS, Kurochkin IV, Mathivanan S, Quesenberry P, Sahoo S, Tahara H, Wauben MH, Witwer KW, Théry C. Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles. Journal of Extracellular Vesicles. 3:26913, 2014

24. Eldh M, Bagge RO, Lässer C, Svanvik J, Sjöstrand M, Mattsson J, Lindnér P, Choi DS, Gho YS, Lötvall J. MicroRNA in exosomes isolated directly from the liver circulation in patients with metastatic uveal melanoma. BMC Cancer. 14(1):962, 2014

25. Kim OY, Choi SJ, Jang SC, Park K, Kim SR, Choi JP, Lim JH, Lee S, Park J, Di Vizio D, Lötvall J, Kim Y, Gho YS. Bacterial protoplast-derived nanovesicles as vaccine delivery system against bacterial infection. Nano Letters. 15(1):266-274, 2015

26. Yoon YJ, Kim DK, Yoon CM, Park J, Kim YK, Roh TY, Gho YS. Egr-1 activation by cancer-derived extracellular vesicles promotes endothelial cell migration via ERK1/2 and JNK signaling pathways. PLoS One. 9(12):e115170, 2014

27. Kim DK, Lee J, Kim SR, Choi DS, Yoon YJ, Kim JH, Go G, Nhung D, Hong K, Jang SC, Kim SH, Park KS, Kim OY, Park HT, Seo JH, Aikawa E, Baj-Krzyworzeka M, van Balkom BW, Belting M, Blanc L, Bond V, Bongiovanni A, Borràs FE, Buée L, Buzás EI, Cheng L, Clayton A, Cocucci E, Dela Cruz CS, Desiderio DM, Di Vizio D, Ekström K, Falcon-Perez JM, Gardiner C, Giebel B, Greening DW, Gross JC, Gupta D, Hendrix A, Hill AF, Hill MM, Nolte-'t Hoen E, Hwang DW, Inal J, Jagannadham MV, Jayachandran M, Jee YK, Jørgensen M, Kim KP, Kim YK, Kislinger T, Lässer C, Lee DS, Lee H, van Leeuwen J, Lener T, Liu ML, Lötvall J, Marcilla A, Mathivanan S, Möller A, Morhayim J, Mullier F, Nazarenko I, Nieuwland R, Nunes DN, Pang K, Park J, Patel T, Pocsfalvi G, Del Portillo H, Putz U, Ramirez MI, Rodrigues ML, Roh TY, Royo F, Sahoo S, Schiffelers R, Sharma S, Siljander P, Simpson RJ, Soekmadji C, Stahl P, Stensballe A, Stępień E, Tahara H, Trummer A, Valadi H, Vella LJ, Wai SN, Witwer K, Yáñez-Mó M, Youn H, Zeidler R, Gho YS. EVpedia: A community web portal for extracellular vesicles research. Bioinformatics. 31(6):933-939, 2015

28. Shelke GV, Lässer C, Gho YS, Lötvall J. Importance of exosome depletion protocols to eliminate functional and RNA-containing extracellular vesicles from fetal bovine serum. Journal of Extracellular Vesicles. 3:24783, 2014

29. Jang SC, Kim SR, Yoon YJ, Park KS, Kim JH, Lee J, Kim OY, Choi EJ, Kim DK, Choi DS, Kim YK, Park J, Di Vizio D, Gho YS. In vivo kinetic biodistribution of nano-sized outer membrane vesicles derived from bacteria. Small. 11(4):456-461, 2015 [Inside front cover]

30. Jo W, Kim J, Yoon J, Jeong D, Cho S, Jeong H, Yoon YJ, Kim SC, Gho YS, Park J. Large-scale generation of cell-derived nanovesicles. Nanoscale. 6(20):12056-12064, 2014

31. Jeong D, Jo W, Yoon J, Kim J, Gianchandani S, Gho YS, Park J. Nanovesicles engineered from ES cells for enhanced cell proliferation. Biomaterials. 35(34):9302-9310, 2014

32. Roh JI, Cheong C, Sung YH, Lee J, Oh J, Lee BS, Lee JE, Gho YS, Kim DK, Park CB, Lee JH, Lee JW, Kang SM, Lee HW. Perturbation of NCOA6 leads to dilated cardiomyopathy. Cell Reports. 8(4):991-998, 2014

33. Yoon YJ, Kim OY, Gho YS. Extracellular vesicles as emerging intercellular communicasomes. BMB Reports. 47(10):531-539, 2014

34. Hong SW, Choi EB, Min TK, Kim JH, Kim MH, Jeon SG, Lee BJ, Gho YS, Jee YK, Pyun BY, Kim YK. An important role of α-hemolysin in extracellular vesicles on the development of atopic dermatitis induced by Staphylococcus aureus. PLoS One. 9(7):e100499, 2014

35. Lee N, Kim DK, Kim ES, Park SJ, Kwon JH, Shin J, Park SM, Moon YH, Wang HJ, Gho YS, Choi KY. Comparative interactomes of SIRT6 and SIRT7: implication of functional links to aging. Proteomics. 14(13-14):1610-1622, 2014

36. Choi EB, Hong SW, Kim DK, Jeon SG, Kim KR, Cho SH, Gho YS, Jee YK, Kim YK. Decreased diversity of nasal microbiota and their secreted extracellular vesicles in patients with chronic rhinosinusitis based on a metagenomic analysis. Allergy. 69(4):517-526, 2014

37. Jang SC, Gho YS. Could bioengineered exosome-mimetic nanovesicles be an efficient strategy for the delivery of chemotherapeutics?. Nanomedicine 9(2):177-180, 2014

38. Jo W, Jeong D, Kim J, Cho S, Jang SC, Han C, Kang JY, Gho YS*, Park J*. Microfluidic fabrication of cell-derived nanovesicles as endogenous RNA carriers. Lab on a Chip.  14(7):1261-1269, 2014 [Inside front cover] [Lab on a Chip 2014 HOT articles] (*co-corresponding authors)

39. Choi DS, Kim DK, Kim YK, Gho YS. Proteomics of extracellular vesicles: exosomes and ectosomes. Mass Spectrometry Reviews. 34(4):474-490, 2015 [Invited review]

40. Jeong J, Park YU, Kim DK, Lee S, Kwak Y, Lee SA, Lee H, Suh YH, Gho YS, Hwang D, Park SK. Cdk5 phosphorylates dopamine d2 receptor and attenuates downstream signaling. PLoS One. 8(12):e84482, 2013

41. Kang CS, Ban M, Choi EJ, Moon HG, Jeon JS, Kim DK, Park SK, Jeon SG, Roh TY, Myung SJ, Gho YS*, Kim JG*, Kim YK*. Extracellular vesicles derived from gut microbiota, especially Akkermansia muciniphila, protect the progression of dextran sulfate sodium-induced colitis. PLoS One. 8(10):e76520, 2013 (*co-corresponding authors)

42. Choi JP, Kim YM, Choi HI, Choi SJ, Park HT, Lee WH, Gho YS, Jee YK, Jeon SG, Kim YK. An important role of tumor necrosis factor receptor-2 on natural killer T cells on the development of dsRNA-enhanced Th2 cell response to inhaled allergens. Allergy. 69(2):186-198, 2014

43. Kim DK, Kang B, Kim OY, Choi DS, Lee J, Kim SR, Go G, Yoon YJ, Kim JH, Jang SC, Park KS, Choi EJ, Kim KP, Desiderio DM, Kim YK, Lötvall J, Hwang D*, Gho YS*. EVpedia: an integrated database of high-thrmoughput data for systemic analyses of extracellular vesicles. Journal of Extracellular Vesicles, 2: 20384, 2013 (*co-corresponding authors)

44. Jang SC, Kim OY, Yoon CM, Choi DS, Roh TY, Park J, Nilsson J, Lötvall J, Kim YK, Gho YS. Bioinspired exosome-mimetic nanovesicles for targeted delivery of chemotherapeutics to malignant tumors. ACS Nano, 7(9):7698-7710, 2013 (Nanomedicine-Invitation to write an editorial: “Could bioengineered exosome-mimetic nanvesicles be an efficient strategy for the delivery of chemotherapeutics?”)

45. Kim Y, Lee S, Kim YS, Lawler S, Gho YS, Kim YK, Hwang HJ. Regulation of Th1/Th2 cells in asthma development: A mathematical model. Mathematical Biosciences and Engineering, 10(4):1095-133, 2013.

46. Yoon YJ, Chang S, Kim OY, Kang BK, Park J, Lim JH, Huang JY, Kim YK, Byun JH, Gho YS. Three-dimensional imaging of hepatic sinusoids in mice using synchrotron radiation micro-computed tomography. PLoS One, 8(7): e68600, 2013

47. Choi DS, Lee J, Go G, Kim YK, Gho YS. Circulating extracellular vesicles in cancer diagnosis and monitoring: An appraisal of clinical potential. Molecular Diagnosis & Therapy. 17: 265-271, 2013 [Invited review]

48. Park KS, Lee J, Jang SC, Kim SR, Jang MH, Lötvall J, Kim YK*, Gho YS*. Pulmonary inflammation induced by bacteria-free outer membrane vesicles from Pseudomonas aeruginosa. American Journal of Respiratory Cell and Molecular Biology, 49(4):637-645 (*co-corresponding authors).

49. Choi H, Lee H, Kim SR, Gho YS, Lee SK. Epstein-Barr virus-encoded microRNA BART15-3p promotes cell apoptosis partially by targeting BRUCE. Journal of Virology, 87: 8135-44, 2013

50. Park JO, Choi DY, Choi DS, Kim HJ, Kang JW, Jung JH, Lee JH, Kim J, Freeman MR, Lee KY, Gho YS*, Kim KP*. Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. Proteomics, 13(14): 2125-2134 (*co-corresponding authors)

51. Lee J, Lee EY, Kim SH, Kim DK, Park KS, Kim KP, Kim YK, Roh TY*, Gho YS* Staphylococcus aureus extracellular vesicles carry biologically active beta-lactamase. Antimicrobial Agents and Chemotherapy, 57: 2589-2595, 2013 (*co-corresponding authors) [F1000 prime recommendations] [Introduced on MDLinx.com]

52. Kim YS, Choi EJ, Lee WH, Choi SJ, Roh TY, Park JS, Jee JK, Zhou Zhu, Koh YY, Gho YS*, Kim YK*. Extracellular vesicles, especially derived from Gram-negative bacteria, in indoor dust induce neutrophilic pulmonary inflammation associated with both Th1 and Th17 cell responses. Clinical and Experimental Allergy, 43: 443-454, 2013 (*co-corresponding authors)

53. Kim JH, Yoon YJ, Lee J, Choi EJ, Yi N, Park KS, Park J, Lötvall J, Kim YK*, Gho YS. Outer membrane vesicles derived from Escherichia coli up-regulate expression of endothelial cell adhesion molecules in vitro and in vivo. PLoS One, 8(3): e59276, 2013 

54. Kim OY, Hong BS, Park KS, Yoon YJ, Choi SJ, Lee WH, Roh TY, Lötvall J, Kim YK, Gho YS. Immunization with Escherichia coli outer membrane vesicles protects bacteria-induced lethality via Th1 and Th17 cell responses. Journal of Immunology. 190(8): 4092-4102, 2013

55. Choi DS, Kim DK, Kim YK, Gho YS. Proteomics, transcriptomics, and lipidomics of exosomes and ectosomes. Proteomics, 13(10-11): 1554-1571, 2013

56. Moon HG, Kang CS, Choi JP, Choi DS, Choi HI, Choi YW, Jeon SG, Yoo JY, Jang MH, Gho YS, Kim YK. Acetyl salicylic acid inhibits Th17 airway inflammation via blockade of IL-6 and IL-17 positive feedback. Experimental & Molecular Medicine, 45: e6, 2013

57. Kalra H, Simpson RJ, Ji H, Aikawa E, Altevogt P, Askenase P, Bond VC, Borràs FE, Breakefield X, Budnik V, Buzas E, Camussi G, Clayton A, Cocucci E, Falcon-Perez JM, Gabrielsson S, Gho YS, Gupta D, Harsha HC, Hendrix A, Hill AF, Inal JM, Jenster G, Krämer-Albers EM, Lim SK, Llorente A, Lötvall J, Marcilla A, Mincheva-Nilsson L, Nazarenko I, Nieuwland R, Nolte-'t Hoen EN, Pandey A, Patel T, Piper MG, Pluchino S, Prasad TS, Rajendran L, Raposo G, Record M, Reid GE, Sánchez-Madrid F, Schiffelers RM, Siljander P, Stensballe A, Stoorvogel W, Taylor D, Thery C, Valadi H, van Balkom BW, Vázquez J, Vidal M, Wauben MH, Yáñez-Mó M, Zoeller M, Mathivanan S. Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. PLoS Biology, 10(12): e1001450, 2012

58. Kim JM, Shin HI, Cha SS, Lee CS, Hong BS, Lim S, Jang HJ, Kim J, Yang YR, Kim YH, Yun S, Rijal G, Lee KW, Seo JK, Gho YS, Ryu SH, Hur EM, Suh PG. DJ-1 promotes angiogenesis and osteogenesis by activating FGF receptor-1 signaling. Nature Communications, 3: 1296, 2012

59. Davies RT, Kim J, Jang SC, Choi EJ, Gho YS, Park J. Microfluidic filtration system to isolate extracellular vesicles from blood. Lab on a Chip, 12(24): 5202-5210, 2012

60. Kim MR, Hong SW, Choi EB, Lee WH, Kim YS, Jeon SG, Jang MH, Gho YS*, Kim YK*. Staphylococcus aureus-derived extracellular vesicles induce neutrophilic pulmonary inflammation via both Th1 and Th17 cell responses. Allergy, 67(10): 1271-1281, 2012 (*co-corresponding authors)

61. Choi JP, Kim YS, Kim OY, Kim YM, Jeon SG, Roh TY, Park JS, Gho YS, Kim YK. TNF-alpha is a key mediator in the development of Th2 cell response to inhaled allergens induced by a viral PAMP double-stranded RNA. Allergy, 67(9): 1138-1148, 2012 

62. Lee EY, Park KS, Yoon YJ, Lee J, Moon HG, Jang SC, Choi KH, Kim YK, Gho YS. Therapeutic effects of autologous tumor-derived nanovesicles on melanoma growth and metastasis. PLoS One, 7(3): e33330, 2012

63. Cheong SM, Choi H, Hong BS, Gho YS, Han JK. Dab2 is pivotal for endothelial cell migration by mediating VEGF expression in cancer cells. Experimental Cell Research, 318(5): 550-557, 2012

64. Tae YM, Park HT, Moon HG, Kim YS, Jeon SG, Roh TY, Bae YS, Gho YS, Ryu SH, Kwon HS, Kim YK. Airway activation of formyl peptide receptors inhibits Th1 and Th17 cell responses via inhibition of mediator release from immune and inflammatory cells and maturation of dendritic cells. Journal of Immunology, 188(4): 1799-1808, 2012

65. Lötvall J, Rajendran L, Gho YS, Théry C, Wauben M, Raposo G, Sjostrand M, Taylor D, Telemo E, Breakefield XO. The launch of Journal of Extracellular Vesicles (JEV), the official journal of the International Society for Extracellular Vesicles – about microvesicles, exosomes, ectosomes, and other extracellular vesicles. Journal of Extracellular Vesicles, 1:18514, 2012.

66. Choi DS, Choi DY, Hong BS, Jang SC, Kim DK, Lee J, Kim YK, Kim KP*, Gho YS*. Quantitative proteomics of extracellular vesicles derived from human primary and metastatic colorectal cancer cells. Journal of Extracellular Vesicles, 1: 18704, 2012 (*co-corresponding authors)

67. Choi DS, Yang JS, Choi EJ, Jang SC, Park S, Kim OY, Hwang D, Kim KP, Kim YK, Kim S, Gho YS. The protein interaction network of extracellular vesicles derived from human colorectal cancer cells. Journal of Proteome Research, 11(2): 1144-1151, 2012

68. Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D*, Gho YS*, Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa. Proteomics, 11(16): 3424-3429, 2011 (*co-corresponding authors)

69. Choi DS, Park JO, Jang SC, Yoon YJ, Jung JW, Choi DY, Kim JW, Kang JS, Park J, Hwang D, Lee KH, Park SH, Kim YK, Desiderio DM, Kim KP*, Gho YS*. Proteomic analysis of microvesicles derived from human colorectal cancer ascites. Proteomics, 11(13): 2745-2751, 2011 (*co-corresponding authors)

70. Lee BJ, Moon HG, Shin TS, Jeon SG, Lee EY, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK. Protective effects of basic fibroblast growth factor in the development of emphysema induced by interferon-gamma. Experimental & Molecular Medicine, 43(4): 169-178, 2011

71. Kim YS, Choi SJ, Tae YM, Lee BJ, Jeon SG, Oh SY, Gho YS, Zhu Z, Kim YK. Distinct roles of vascular endothelial growth factor receptor-1- and receptor-2-mediated signaling in T cell priming and Th17 polarization to lipopolysaccharide-containing allergens in the lung. Journal of Immunology. 185(9): 5648-5655, 2010

72. Shin TS, Lee BJ, Tae YM, Kim YS, Jeon SG, Gho YS, Choi DC, Kim YK. Role of inducible nitric oxide synthase on the development of virus-associated asthma exacerbation which is dependent on Th1 and Th17 cell responses. Experimental & Molecular Medicine, 42(10): 721-730, 2010

73. Hong SW, Kim MR, Lee EY, Kim JH, Kim YS, Jeon SG, Yang JM, Lee BJ, Pyun BY, Gho YS*, Kim YK*. Extracellular vesicles derived from Staphylococcus aureus induce atopic dermatitis-like skin inflammation. Allergy, 66(3): 351-359, 2011 (*co-corresponding authors)

74. Park KS, Choi KH, Kim YS, Hong BS, Kim OY, Kim JH, Yoon CM, Koh GY, Kim YK*, Gho YS*. Outer membrane vesicles derived from Escherichia coli induce systemic inflammatory response syndrome. PLoS One, 5(6): e11334, 2010 (*co-corresponding authors)

75. Kim YS, Choi SJ, Choi JP, Jeon SG, Oh SY, Lee BJ, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK. IL-12-STAT4-IFN-gamma axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model. Experimental & Molecular Medicine, 42(8): 533-546, 2010

76. Kim JW, Kim TD, Hong BS, Kim OY, Yoon WH, Chae CB, Gho YS. A serum-stable branched dimeric anti-VEGF peptide blocks tumor growth via anti-angiogenic activity. Experimental & Molecular Medicine, 42(7): 514-523, 2010

77. Lee HM, Choi EJ, Kim JH, Kim TD, Kim YK, Kang C, Gho YS. A membranous form of ICAM-1 on exosomes efficiently blocks leukocyte adhesion to activated endothelial cells. Biochemical and Biophysical Research Communications, 397(2): 251-256, 2010

78. Choi JP, Kim YS, Tae YM, Choi EJ, Hong BS, Jeon SG, Gho YS, Zhu Z, Kim YK. A viral PAMP double-stranded RNA induces allergen-specific Th17 cell response in the airways which is dependent on VEGF and IL-6. Allergy. 65(10): 1322-1330, 2010

79. Moon HG, Tae YM, Kim YS, Gyu Jeon S, Oh SY, Gho YS, Zhu Z, Kim YK. Conversion of Th17-type into Th2-type inflammation by acetyl salicylic acid via the adenosine and uric acid pathway in the lung. Allergy. 65(9): 1093-1103, 2010

80. Shin TS, Kim JH, Kim YS, Jeon SG, Zhu Z, Gho YS*, Kim YK*. Extracellular vesicles are key intercellular mediators in the development of immune dysfunction to allergens in the airways. Allergy. 65(10): 1256-1265, 2010 (*co-corresponding authors)

81. Hong BS, Cho JH, Kim H, Choi EJ, Rho S, Kim J, Kim JH, Choi DS, Kim YK, Hwang D*, Gho YS*. Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells. BMC Genomics, 10: 556, 2009 (*co-corresponding authors)

82. Moon HG, Kim YS, Choi JP, Choi DS, Yoon CM, Jeon SG, Gho YS*, Kim YK*. Aspirin attenuates the anti-inflammatory effects of theophylline via inhibition of cAMP production in mice with non-eosinophilic asthma. Experimental & Molecular Medicine 42(1): 47-60, 2010 (*co-corresponding authors)

83. Lee EY, Choi DY, Kim DK, Kim JW, Park JO, Kim S, Kim SH, Desiderio DM, Kim YK, Kim KP*, Gho YS*. Gram-positive bacteria produce membrane vesicles: proteomics-based characterization of Staphylococcus aureus-derived membrane vesicles. Proteomics, 9(24): 5425-5436, 2009 (*co-corresponding authors)

84. Kim YS, Hong SW, Choi JP, Shin TS, Moon HG, Choi EJ, Jeon SG, Oh SY, Gho YS, Zhu Z, Kim YK. Vascular endothelial growth factor is a key mediator in the development of T cell priming and its polarization to type 1 and type 17 T helper cells in the airways. Journal of Immunology, 183(8): 5113-5120, 2009

85. Kim SH, Kim KS, Lee SR, Kim E, Kim MS, Lee EY, Gho YS, Kim JW, Bishop RE, Chang KT. Structural modifications of outer membrane vesicles to refine them as vaccine delivery vehicles. Biochimica et Biophysica Acta, 1788(10): 2150-2159, 2009

86. Kwon SO, Gho YS, Lee JC, Kim SI. Proteome analysis of outer membrane vesicles from a clinical Acinetobacter baumannii isolate. FEMS Microbiol Letters, 297(2): 150-156, 2009

87. Jeon SG, Moon HG, Kim YS, Choi JP, Shin TS, Hong SW, Tae YM, Kim SH, Zhu Z, Gho YS, Kim YK. 15-lipoxygenase metabolites play an important role in the development of a T-helper type 1 allergic inflammation induced by double-stranded RNA. Clinical & Experimental Allergy, 39(6): 908-917, 2009

88. Yoon CM, Hong BS, Moon HG, Lim S, Suh PG, Kim YK, Chae CB, Gho YS. Sphingosine-1-phosphate promotes lymphangiogenesis by stimulating S1P1/Gi/PLC /Ca2+ signaling pathways. Blood, 112(4): 1129-1138, 2008

89. Kim GB, Yoon YJ, Shin TJ, Youn HS, Gho YS, Lee SJ. X-ray imaging of various biological samples using a phase-contrast hard X-ray microscope. Microscopic Research and Technique, 71(9): 639-643, 2008

90. Lee EY, Choi DS, Kim KP, Gho YS. Proteomics in Gram-negative bacterial outer membrane vesicles. Mass Spectrometry Reviews, 27(6): 535-555, 2008 [Invited review]

91. Park HK, Park HW, Jeon SG, Shin ES, Gho YS, Cho SH, Kim YY, Kim YK. Distinct association of genetic variations of vascular endothelial growth factor, transforming growth factor-beta, and fibroblast growth factor receptors with atopy and airway hyperresponsiveness. Allergy, 63(4): 447-453, 2008

92. Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS. Proteomic analysis of microvesicles derived from human colorectal cancer cells. Journal of Proteome Research, 12 6(12): 4646-4655, 2007

93. Lee EY, Bang JY, Park GW, Choi DS, Kang JS, Kim HJ, Park KS, Lee JO, Kim YK, Kwon KH, Kim KP, Gho YS. Global proteomic profiling of native outer membrane vesicles derived from Escherichia coli. Proteomics, 7(17): 3143-3153, 2007 [Cover story]

94. Lee KH, Yun SJ, Nam KN, Gho YS, Lee EH. Activation of microglial cells by ceruloplasmin. Brain Research, 1171: 1-8, 2007

95. Jeon SG, Oh SY, Park HK, Kim YS, Shim EJ, Lee HS, Oh MH, Bang B, Chun EY, Kim SH, Gho YS, Zhu Z, Kim YY, Kim YK. T(H)2 and T(H)1 lung inflammation induced by airway allergen sensitization with low and high doses of double-stranded RNA. The Journal of Allergy and Clinical Immunology, 120(4): 803-812, 2007

96. Han KY, Hong BS, Yoon YJ, Yoon CM, Kim YK, Kwon YG, Gho YS.  Polyphosphate blocks tumour metastasis via anti-angiogenic activity. The Biochemical Journal, 406(1): 49-55, 2007 [F1000 prime recommendations]

97. Kim YK, Park HW, Yang JS, Oh SY, Chang YS, Shin ES, Lee JE, Kim SU, Gho YS, Cho SH, Min KU, Kim YY. Association and functional relevance of E237G, a polymorphism of the high-affinity IgE-Receptor beta chain gene, to airway hyperresponsiveness. Clinical & Experimental Allergy, 37(4): 592-598, 2007

98. Kim YK, Oh SY, Jeon SG, Park HW, Lee SY, Chun EY, Bang B, Lee HS, Oh MH, Kim YS, Kim JH, Gho YS, Cho SH, Min KU, Kim YY, Zhu Z. Airway exposure levels of lipopolysaccharide determine type 1 versus type 2 experimental asthma. Journal of Immunology, 178(11): 5375-5382, 2007

99. Kim KY, Oh HB, Lee EY, Gho YS, Lee JE, Kim YY. Association between a genetic variation of CC chemokine receptor-2 and atopic asthma. Allergy. 62(2):208-209, 2007

100. Jeon SG, Lee CG, Oh MH, Chun EY, Gho YS, Cho SH, Kim JH, Min KU, Kim YY, Kim YK, Elias JA. Recombinant basic fibroblast growth factor inhibits the airway hyper-responsiveness, mucus production, and lung inflammation induced by an allergen challenge. The Journal of Allergy and Clinical Immunology, 119(4): 831-837, 2007 [F1000 prime recommendations]

101. Byon HR, Hong BJ, Gho YS, Park JW, Choi HC. Pseudo 3D single-walled carbon nanotube film for BSA-free protein chips. Chembiochem, 6(8): 1331-1334, 2005

102. Hwang J, Son KN, Kim CW, Ko J, Na DS, Kwon BS, Gho YS*, Kim J*. Human CC chemokine CCL23, a ligand for CCR1, induces endothelial cell migration and promotes angiogenesis. Cytokine, 30(5): 254-263, 2005 (*co-corresponding authors)

103. Yang SP, Kwon BO, Gho YS, Chae CB. Specific interaction of VEGF165 with beta-amyloid, and its protective effect on beta-amyloid-induced neurotoxicity. Cytokine, 30(5): 254-263, 2005

104. Min JK, Lee YM, Kim JH, Kim YM, Kim SW, Lee SY, Gho YS, Oh GT, Kwon YG. Hepatocyte growth factor suppresses vascular endothelial growth factor-induced expression of endothelial ICAM-1 and VCAM-1 by inhibiting the nuclear factor-kappaB pathway. Circulation Research, 96(3): 300-307, 2005

105. Hahm ER, Gho YS, Park S, Park C, Kim KW, Yang CH. Synthetic curcumin analogs inhibit activator protein-1 transcription and tumor-induced angiogenesis. Biochemical and Biophysical Research Communications, 321(2): 337-344, 2004

106. Hwang J, Kim CW, Son KN, Han KY, Lee KH, Kleinman HK, Ko J, Na DS, Kwon BS, Gho YS*, Kim J*.  Angiogenic activity of human CC chemokine CCL15 in vitro and in vivo. FEBS Letters, 570(1-3): 47-51, 2004 (*co-corresponding authors)

107. Yang SP, Bae DG, Kang HJ, Gwag BJ, Gho YS*, Chae CB*. Co-accumulation of vascular endothelial growth factor with beta-amyloid in the brain of patients with Alzheimer's disease. Neurobiology of Aging, 25(3): 283-290, 2004 (*co-corresponding authors)

108. Lee SJ, Lee HM, Ji ST, Lee SR, Mar W, Gho YS. 1,2,3,4,6-penta- O-galloyl-beta-D-glucose blocks endothelial cell growth and tube formation through inhibition of VEGF binding to VEGF receptor. Cancer Letters, 208(1): 89-94, 2004

109. Min JK, Han KY, Kim EC, Kim YM, Lee SW, Kim OH, Kim KW, Gho YS, Kwon YG. Capsaicin inhibits in vitro and in vivo angiogenesis. Cancer Research, 64(2): 644-651, 2004

110. Philp D, Huff T and Gho YS, Hannappel E, Kleinman HK. The actin binding site on thymosin beta4 promotes angiogenesis. FASEB Journal, 17(14): 2103-2105, 2003

111. Min JK, Kim YM, Kim YM, Kim EC, Gho YS, Kang IJ, Lee SY, Kong YY, Kwon YG. Vascular endothelial growth factor up-regulates expression of receptor activator of NF-kappa B (RANK) in endothelial cells. Concomitant increase of angiogenic responses to RANK ligand. Journal of Biological Chemistry, 278(41): 39548-39557, 2003

112. Kim CW, Lee HM, Lee TH, Kang C, Kleinman HK, Gho YS. Extracellular membrane vesicles from tumor cells promote angiogenesis via sphingomyelin. Cancer Research, 62(21): 6312-6317, 2002

113. Cid MC, Hernández-Rodríguez J, Esteban MJ, Cebrián M, Gho YS, Font C, Urbano-Márquez A, Grau JM, Kleinman HK. Tissue and serum angiogenic activity is associated with low prevalence of ischemic complications in patients with giant-cell arteritis. Circulation, 106(13): 1664-1671, 2002

114. Kim YM, Hwang S, Kim YM, Pyun BJ, Kim TY, Lee ST, Gho YS*, Kwon YG*. Endostatin blocks VEGF-mediated signaling via direct interaction with KDR/Flk-1. Journal of Biological Chemistry, 277(31): 27872-27879, 2002 (*co-corresponding authors) 

115. Gho YS, Yoon WH, Chae CB. Anti-plasmin activity of a complementary peptide to the receptor-binding site of angiogenin. Journal of Biological Chemistry, 277(12): 9690-9694, 2002

116. Gho YS, Kim PN, Li HC, Elkin M, Kleinman HK. Stimulation of tumor growth by human soluble intercellular adhesion molecule-1. Cancer Research, 61(10): 4253-4257, 2001

117. Nielsen PK, Gho YS, Hoffman MP, Watanabe H, Makino M, Nomizu M, Yamada Y. Identification of a major heparin and cell binding site in the LG4 module of the laminin alpha 5 chain. Journal of Biological Chemistry, 275(19): 14517-14523, 2000

118. Bae DG, Gho YS, Yoon WH, Chae CB. Arginine-rich anti-vascular endothelial growth factor peptides inhibit tumor growth and metastasis by blocking angiogenesis. Journal of Biological Chemistry, 275(18): 13588-13596, 2000

119. Gho YS, Kleinman HK, Sosne G. Angiogenic activity of human soluble intercellular adhesion molecule-1 (sICAM-1). Cancer Research, 59(20): 5128-5132, 1999

120. Boykins RA, Mahieux R, Shankavaram UT, Gho YS, Lee SF, Hewlett IK, Wahl LM, Kleinman HK, Brady JN, Yamada KM, Dhawan S. Cutting edge: a short polypeptide domain of HIV-1-Tat protein mediates pathogenesis. Journal of Immunology, 163(1): 15-20, 1999

121. Gho YS, Chae CB. Luteinizing hormone releasing hormone-RNase A conjugates specifically inhibit the proliferation of LHRH-receptor-positive human prostate and breast tumor cells. Molecules and Cells, 9(1): 31-36, 1999

122. Gho YS, Chae CB. Anti-angiogenin activity of the peptides complementary to the receptor-binding site of angiogenin. Journal of Biological Chemistry, 272(39): 24294-24299, 1997

123. Gho YS, Lee JE, Oh KS, Bae DG, Chae CB. Development of antiangiogenin peptide using phage-displayed peptide library. Cancer Research, 57(17): 3733-3740, 1997


Copyright 2006 (c) Lab. of Intercellular Communication Network,
Deptartment of Life Science, POSTECH San 31 Hyojadong, Pohang, Kyoungbuk, 790-784, Republic of Korea
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